HPLC Columns

HPLC Column with ELI-chip, zero dead volume

HPLC Column with the ELI-chip as ionization source. By placing the compact ELI-chip directly at the end of the column, unnecessary dead volume is eliminated, effectively minimizing peak broadening. The eluent, which typically is low in salts, has a low electric conductivity, something that is problematic for direct ionization methods such as ESI. Electroless ionization (ELI) however, with its fundamentally different ionization mechanism works best for such solvents. The number of holes on the chip and the liquid pressure can be adapted to reach the desired flow rate.